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OB/GYN
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CIN 3 Management
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Excisional treatment then surveillance.
Decision
Outcome
Decision
CIN 3 in non-pregnant patient — first-line treatment?
✓
Excisional procedure: LEEP or cold-knife conization (alt: cryoablation)
✗
Hysterectomy
Decision
After treatment — surveillance?
✓
Pap with HPV co-testing 1 and 2 years post-procedure
Outcome
If co-testing positive, repeat colposcopy
Cold-knife conization preferred if invasive cancer suspected or fertility-preserving with adequate margin.